var voice = './sound/14t888piCqei.mp3';
var voice = new Audio(voice);
voice.play(); //播放

chrome >=66 不支持音频自动播放
Uncaught (in promise) DOMException: play() failed because the user didn't interact with the document first.

降级处理不播放

function soundPlay () {
    // 返回一个promise以告诉调用者检测结果
    return new Promise(resolve => {
        let audio = document.createElement('audio');
        audio.src = '../dist/sound/14t888piCqei.mp3';
        document.body.appendChild(audio);
        let autoplay = true;
        // play返回的是一个promise
        audio.play().then(() => {
            // 支持自动播放
            autoplay = true;
        }).catch(err => {
            // 不支持自动播放
            autoplay = false;
        }).finally(() => {
            // 告诉调用者结果
            resolve(autoplay);
        });
    });
}

WebSocket轮询消息，提示声音，git：https://github.com/vagsy/websocket

参考：

js加载音频文件并播放，代码实例

Chrome 66禁止声音自动播放之后